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ACOG, SGO and ASCCP support Primary HPV Screening
in women 25 years and older.1,4

cobas® HPV Test the only approved test for ASC-US reflex, Co-testing, and Primary Screening

ACOG supports HPV Primary Screening

Revised Practice Bulletin 157 reinforces 2015 interim guidance issued by Society for Gynecologic Oncology (SGO) and the American Society for Colposcopy and Cervical Pathology (ASCCP).1,4

New Guidance 

A new paradigm in the fight against cervical cancer

HPV primary screening algorithm identifies more high grade disease than a Pap test alone and maintains screening efficiency.

The Case for Primary Screening 

Normal cytology doesn't always mean cancer free.

Up to one third of cervical cancers occur in screened women.2,3 Invasive cervical cancer occurs in women with normal Pap cytology.

Understanding the Limitations of Pap 
  • Acronyms:



  1. SGO Press Release January 2015
  2. Leyden WA, Manos MM, Geiger AM, et al. Cervical cancer in women with comprehensive health care access: attributable factors in the screening process. J Natl Cancer Inst. 2005;97(9):675-683.
  3. Andrae B, Kemetli L, Sparén P, et al. Screening-preventable cervical cancer risks: evidence from a nationwide audit in Sweden.J Natl Cancer Inst. 2008;100(9):622-629.
  4. ACOG Practice Bulletin 157; January 2016