ACOG guidelines summary
The following recommendations are based on good and consistent scientific evidence (Level A):1
- Cervical cancer screening should begin at age 21 years.
- Pap cytology screening is recommended every 3 years for women between the ages of 21 years and 29 years.
- For women aged 30-65 years, co-testing with cervical cytology screening and HPV testing is preferred and should be performed every 5 years.
- For women aged 30-65 years, screening with cytology alone every 3 years is acceptable.
- Both liquid-based and conventional methods of Pap cytology are acceptable for screening.
- In women who have had a total hysterectomy and have never had CIN2 or higher, routine cytology screening and HPV testing should be discontinued and not restarted for any reason.
- Women who have a history of cervical cancer, have HIV infection, are immunocompromised, or were exposed to diethylstilbestrol in utero should not follow routine screening guidelines.
- Screening by any modality should be discontinued after age 65 years in women with evidence of adequate negative prior screening results* and no history of CIN2 or higher
*Adequate negative prior screening results are defined as three consecutive negative cytology results or two consecutive negative co-test results within the previous 10 years, with the most recent test performed within the past 5 years.